HLA-alleles class I and II associated with genetic susceptibility to neuromyelitis optica in Brazilian patients.
Cláudia Suemi Kamoi KayRosana Hermínia ScolaRaquel Cristina ArndtPaulo José LorenzoniLineu Cesar WerneckPublished in: Arquivos de neuro-psiquiatria (2020)
In our study, the HLA genotype was different to that previously reported for other Brazilian populations. Although our study had a small cohort, HLA genotypes were associated with increased susceptibility to NMO for HLA-DRB1*04:05 and *16:02. The alleles of HLA class I HLA-A*02:08 and *30:09, HLA-B*08:04 and *35:04 showed an association before the Bonferroni correction.