Risk factor associations for severe COVID-19, influenza and pneumonia in people with diabetes to inform future pandemic preparations: UK population-based cohort study.
Rhian HopkinsKatherine G YoungNicholas J ThomasJames GodwinDaniyal RajaBilal A MateenRobert J ChallenSebastian J VollmerBeverley M ShieldsAndrew P McGovernRaphael SonabendPublished in: BMJ open (2024)
Clinical risk factors of high HbA1c and severe obesity are consistently associated with severe outcomes from COVID-19, influenza and pneumonia, especially in younger people. In contrast, associations with sociodemographic risk factors differed by type of respiratory infection. This emphasises that risk stratification should be specific to individual respiratory infections.
Keyphrases
- risk factors
- coronavirus disease
- sars cov
- type diabetes
- early onset
- metabolic syndrome
- magnetic resonance
- insulin resistance
- respiratory syndrome coronavirus
- magnetic resonance imaging
- weight gain
- computed tomography
- physical activity
- current status
- glycemic control
- intensive care unit
- adipose tissue
- respiratory failure
- skeletal muscle
- mechanical ventilation
- high fat diet induced