Pulmonary diffuse lymphoid hyperplasia (DLH), a nonneoplastic lymphoproliferative disorder (LPD), is extremely rare, and no PET/CT findings have been reported for pulmonary DLH. We observed slowly expanding irregular opacities with 18 F-FDG accumulation (SUV max , 3.64) in the right lower lobe of a 51-year-old asymptomatic man. The patient underwent video-assisted thoracoscopic biopsy on suspicion of malignant lesions. Histologically, no neoplastic cells were present, and the lesion was consistent with DLH. Six months later, the patient developed rheumatoid arthritis. DLH should be considered in the differentiation of PET-positive irregular opacities, even in the absence of known immune abnormalities.
Keyphrases
- pet ct
- rheumatoid arthritis
- positron emission tomography
- pulmonary hypertension
- case report
- induced apoptosis
- low grade
- disease activity
- cell cycle arrest
- interstitial lung disease
- computed tomography
- epstein barr virus
- ankylosing spondylitis
- endoplasmic reticulum stress
- signaling pathway
- oxidative stress
- ultrasound guided
- thoracic surgery