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Methylation status of vault RNA 2-1 promoter is a predictor of glycemic response to glucagon-like peptide-1 analog therapy in type 2 diabetes mellitus.

Chia-Hung LinYun-Shien LeeYu-Yao HuangChi-Neu Tsai
Published in: BMJ open diabetes research & care (2021)
The glycemic response to GLP-1 analog treatment is associated with the methylation status of the VTRNA2-1 promoter and polymorphism of rs2346018.
Keyphrases
  • dna methylation
  • type diabetes
  • genome wide
  • gene expression
  • transcription factor
  • glycemic control
  • stem cells
  • combination therapy
  • insulin resistance
  • cell therapy