Malignant transformation of oral leukoplakia: a follow-up study.

Primali Rukmal JayasooriyaKitmini DayaratneUpul Bandara DissanayakeSaman Warnakulasuriya

Published in: Clinical oral investigations (2020)

Leukoplakias (7.5%) transformed over a mean follow-up period of 30 months. Dysplasia grading and the clinical appearance by colour (mixed white and red) were significant predictors of malignant transformation CLINICAL SIGNIFICANCE: Patients with erythroleukoplakia and those diagnosed with moderate or severe epithelial dysplasia require more intensive interventions as such lesions have a higher risk of developing a malignancy.

Keyphrases

physical activity
early onset
high intensity
drug induced