PCSK9 loss-of-function variants and risk of infection and sepsis in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) cohort.

Kellie A MitchellJustin Xavier MooreRobert S RosensonRyan IrvinFaheem W GuirgisNathan ShapiroMonika SaffordHenry E Wang

Published in: PloS one (2019)

PCSK9 LOF variants are not associated with increased risk of hospitalization for a serious infection. Among those hospitalized for a serious infection, PCSK9 LOF variants was not associated with odds of sepsis.

Keyphrases

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intensive care unit
acute kidney injury
septic shock
atrial fibrillation
dna methylation
blood brain barrier
cerebral ischemia