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Development of the Kazakhstan Y-chromosome haplotype reference database: analysis of 27 Y-STR in Kazakh population.

Maxat ZhabaginAliya SarkytbayevaInkar TazhigulovaDauren YerezhepovSvetlana LiRakhmetolla AkilzhanovAlibek YeralinovZhaxylyk SabitovAinur Akilzhanova
Published in: International journal of legal medicine (2018)
To improve available databases of forensic interest, all Y-STR haplotypes from Kazakh population were presented in this study. The reference database accumulated almost 3650 samples from academic and citizen science. Additionally, 27 Y-STR from Yfiler Plus System were first analyzed in 300 males from Kazakh (Qazaq) populations residing in Kazakhstan. The data is available in the YHDR under accession numbers YA004316 and YA004322. A total of 270 unique haplotypes were observed. Discrimination capacity was 90%. Obtained Y-STR haplotypes exhibited a high intra-population diversity. Analysis of pairwise genetic distances showed lowest RST values from Uighur and Mongolian populations.
Keyphrases
  • public health
  • genome wide
  • electronic health record
  • medical students
  • artificial intelligence