Proton pump inhibitors alter the composition of the gut microbiota.
Matthew A JacksonJulia K GoodrichMaria-Emanuela MaxanDaniel E FreedbergJulian A AbramsAngela C PooleJessica L SutterDaphne WelterRuth E LeyJordana T BellTim D SpectorClaire J StevesPublished in: Gut (2015)
Our findings describe a significant impact of PPIs on the gut microbiome and should caution over-use of PPIs, and warrant further investigation into the mechanisms and their clinical consequences.
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