The distributions of protein coding genes within chromatin domains in relation to human disease.

Enrique M MuroJonas Ibn-SalemMiguel A Andrade-Navarro

Published in: Epigenetics & chromatin (2019)

Genes associated with human disease do not distribute randomly over the TADs. Our observations suggest general rules that confer functional stability to TADs, adding more evidence to the role of TADs as regulatory units.

Keyphrases

endothelial cells
transcription factor
induced pluripotent stem cells
genome wide
gene expression
dna damage
protein protein