Hyperlipidemia Alters the Pharmacokinetics of Posaconazole and Vincristine Upon Co-Administration in Rats.

Hadeel A KhalilMohammed A W ElKhatibTarek S BelalAhmed F El-YazbiDalia A Hamdy

Published in: Drugs in R&D (2018)

Monitoring cholesterol and triglyceride levels in patients with acute lymphoblastic leukemia is advisable to decrease VCR neurological side effect incidences and delay the activity of both PSZ and VCR.

Keyphrases

acute lymphoblastic leukemia
low density lipoprotein
high fat diet
type diabetes
metabolic syndrome
blood brain barrier
cerebral ischemia