Endometriosis with infertility: A comprehensive review on the role of immune deregulation and immunomodulation therapy.

Arsenne MekinianJaume Alijotas-ReigJonathan CohenMeryem CheloufiLise SelleretEmmanuelle d'ArgentGilles KayemEnrique E ValverdeOlivier FainMarie BornesEmile DaraiArsene Mekinian

Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2020)

Endometriosis is characterized by increased levels of cytokines and autoantibodies. This suggests the role of inflammation and immune cell deregulation in infertility associated with endometriosis. The strategies of immunomodulation to regulate these immune deregulations are poorly studied, and well-designed studies are necessary.

Keyphrases

oxidative stress
systemic lupus erythematosus
polycystic ovary syndrome
stem cells
metabolic syndrome
adipose tissue
insulin resistance
skeletal muscle
cell therapy