Heart Rate reduction by IVabradine for improvement of ENDothELial function in patients with coronary artery disease: the RIVENDEL study.
Fabio MangiacapraIginio ColaioriElisabetta RicottiniFrancesco BalducciAntonio CretaChiara DemartiniGiorgio MinottiGermano Di SciascioPublished in: Clinical research in cardiology : official journal of the German Cardiac Society (2016)
In patients with CAD undergoing complete revascularization with PCI, addition of ivabradine to the standard medical therapy produces a significant improvement in endothelial function. This effect seems to be related to HR reduction. ClinicalTrials.gov number, NCT02681978.