JTE-013 supplementation partially improved erectile function in rats with DMED, likely by inhibiting smooth muscle contraction, corporal fibrosis, and apoptosis.
Keyphrases
- smooth muscle
- diabetic rats
- oxidative stress
- type diabetes
- endoplasmic reticulum stress
- cell cycle arrest
- cell death
- high glucose
- protein kinase
- signaling pathway
- cardiovascular disease
- high fat diet
- glycemic control
- pi k akt
- tyrosine kinase
- liver fibrosis
- insulin resistance
- drug induced
- diabetic nephropathy
- benign prostatic hyperplasia