High somatostatin receptor expression and efficacy of somatostatin analogues in patients with metastatic Merkel cell carcinoma.
Tomoko AkaikeJamiluddin J QaziA AndersonF S BehniaM M ShinoharaGensuke AkaikeDaniel S HippeH ThomasSeesha R TakagishiK LachanceS Y ParkE S TarabadkarJ G IyerA BlomU ParvathaneniH VessellePaul T NghiemShailender BhatiaPublished in: The British journal of dermatology (2020)
In contrast to other high-grade NETs, mMCC tumours appear frequently to express SSTRs. SSAs can lead to clinically meaningful disease control with minimal side-effects. Targeting of SSTRs using SSA or other novel approaches should be explored further for mMCC.