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Yeast extracts from different manufacturers and supplementation of amino acids and micro elements reveal a remarkable impact on alginate production by A. vinelandii ATCC9046.

Sarah SparvieroMax Daniel DickeTobias M RoschTania CastilloHoljes Salgado-LugoEnrique GalindoCarlos PeñaJochen Büchs
Published in: Microbial cell factories (2023)
The choice of yeast extract is crucial for A. vinelandii cultivations, to maintain reproducibility and comparability between cultivations. The proper use of specific yeast extracts allows the cultivation results to be specifically optimised. In addition, supplements can be applied to modify and improve the properties of the alginate. The results only scratch the surface of the underlying mechanisms, as they are not providing explanations on a molecular level. However, the findings show the potential of optimising media containing yeast extract for alginate production with A. vinelandii, as well as the potential of targeted supplementation of the media.
Keyphrases
  • saccharomyces cerevisiae
  • cell wall
  • oxidative stress
  • amino acid
  • wound healing
  • human health
  • cancer therapy
  • risk assessment
  • gene expression
  • single cell
  • genome wide
  • decision making