Grape seed extract effects on hippocampal neurogenesis, synaptogenesis and dark neurons production in old mice. Can this extract improve learning and memory in aged animals?

Seyed Hamidreza Rastegar-MoghaddamMaryam BighamMahmoud HosseiniAlireza Ebrahimzadeh-BideskanAmir Mohammad MalvandiAbbas Mohammadipour

Published in: Nutritional neuroscience (2021)

Consuming GSE in the elderly can potentially alleviate the age-related reduction of hippocampal neurogenesis and synaptogenesis. It is also able to decrease hippocampal DNs production and increase memory and learning.

Keyphrases

cerebral ischemia
subarachnoid hemorrhage
oxidative stress
blood brain barrier
temporal lobe epilepsy
brain injury
spinal cord
middle aged
type diabetes
adipose tissue
high fat diet induced
metabolic syndrome