Cholinergic Basal Forebrain Volumes Predict Gait Decline in Parkinson's Disease.
Joanna WilsonAlison J YarnallChesney E CraigBrook GalnaSue LordRosie MorrisRachael A LawsonLisa AlcockGordon W DuncanTien K KhooJohn T O'BrienDavid J BurnJohn-Paul TaylorNicola J RayLynn RochesterPublished in: Movement disorders : official journal of the Movement Disorder Society (2020)
This is the first study to demonstrate that degeneration of the cortical cholinergic system predicts longitudinal progression of gait impairments in PD. Measures of this degeneration may therefore provide a novel biomarker for identifying future mobility loss and falls. © 2020 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Keyphrases