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Pharmacokinetics, feasibility and safety of co-administering azithromycin, albendazole, and ivermectin during mass drug administration: A review.

Scott McPhersonAnthony W SolomonFikre SeifeHiwot SolomonTeshome GebreDavid C W MabeyMichael Marks
Published in: PLoS neglected tropical diseases (2023)
There are relatively limited data on the safety profile of co-administering ivermectin, albendazole and azithromycin as an integrated regimen for NTDs. Despite the limited amount of data, available evidence suggests that such a strategy is safe with an absence of clinically important drug-drug interactions, no serious adverse events reported and little evidence for an increase in mild adverse events. Integrated MDA may be a viable strategy for national NTD programmes.
Keyphrases
  • drug administration
  • electronic health record
  • big data
  • breast cancer cells
  • quality improvement
  • adverse drug
  • signaling pathway