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Cardio-ankle vascular index and circulating CD34-positive cell levels as indicators of endothelial repair activity in older Japanese men.

Yuji ShimizuHirotomo YamanashiYuko NoguchiJun KoyamatsuMako NagayoshiKairi KiyouraShoichi FukuiMami TamaiShin-Ya KawashiriHideaki KondoTakahiro Maeda
Published in: Geriatrics & gerontology international (2019)
As circulating CD34-positive cell count might indicate endothelial repair activity, the present results show that CAVI is affected by insufficient endothelial repair in individuals with low circulating CD34-positive cell counts. Our results also show that a positive association between CAVI and carotid intima-media thickness exists only in individuals with aggressive endothelial repair, which indicates the presence of organic arterial disease, such as atherosclerosis. Geriatr Gerontol Int 2019; 19: 557-562.
Keyphrases
  • endothelial cells
  • single cell
  • cell therapy
  • type diabetes
  • physical activity
  • metabolic syndrome
  • stem cells
  • peripheral blood