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Modeling Costs and Life-Years Gained by Population-Wide Next-Generation Sequencing or Single-Gene Testing in Nonsquamous Non-Small-Cell Lung Cancer in the United States.

Christopher A LemmonJie ZhouBrian P HobbsNathan A Pennell
Published in: JCO precision oncology (2023)
On the basis of current evidence, population-level simulations demonstrate that clinically relevant gains in survival with non-negligible reduction in costs are obtainable from widespread adoption of NGS testing and appropriate treatment matching for patients with advanced nonsquamous non-small-cell lung cancer.
Keyphrases
  • copy number
  • genome wide
  • molecular dynamics
  • electronic health record
  • gene expression