mGluR1/IP3/ERK signaling pathway regulates vestibular compensation in ON UBCs of the cerebellar flocculus.

Dan Liu Jun WangE TianJingyu ChenWeijia KongYisheng Lu Su-Lin Zhang

Published in: CNS neuroscience & therapeutics (2023)

mGluR1α activity in cerebellar ON UBC is crucial for mediating VC through the mGluR1/IP3/ERK signaling pathway, which affects ON UBC neuron activity and contributes to the pathogenesis of VC.

Keyphrases

signaling pathway
pi k akt
induced apoptosis
epithelial mesenchymal transition
cell proliferation
oxidative stress
endoplasmic reticulum stress