Incidence and outcomes of patients with atrial fibrillation and major bleeding complications: from the TREAT-AF study.
Alexander C PerinoDaniel W KaiserRandall J LeeJun FanMariam AskariSusan K SchmittMintu P TurakhiaPublished in: Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing (2020)
Development of contraindication to OAC after diagnosis of AF is common (11.5%), with most events requiring hospitalization. OAC reinitiation was associated with non-intracranial bleeding risk, with a trend toward reduced stroke risk. These data suggest that stroke prevention approaches after major bleeding events could be beneficial if bleeding risk can be successfully mitigated.