Nonsteroidal Anti-Inflammatory Drugs Impact on the Outcomes of Hospitalized Patients with Clostridium difficile Infection.
Harish K PatelJasbir MakkerTrupti VakdeDanial ShaikhKanthi BadipatlaJames DunneNikhitha MantriSuresh Kumar NayuduMariela GlandtBhavna BalarSridhar ChilimuriPublished in: Clinical and experimental gastroenterology (2019)
This retrospective study results, contrary to mouse model, did not show association between NSAID use and CDI related mortality and toxic mega-colon. Shorter duration of NSAIDs use, younger people in study group, and timely CDI treatment may have resulted in contrasting results.