A Novel TNFSF-Based Signature Predicts the Prognosis and Immunosuppressive Status of Lower-Grade Glioma.

Rui Tao Qi LiuRuoyu HuangKuanyu WangZhiyan SunPei Yang Jiangfei Wang

Published in: BioMed research international (2022)

Our signature could accurately predict the prognosis of lower-grade gliomas (LGG). In addition, this six-gene signature could predict the immunosuppressive status of LGG and provide evidence that TNF superfamilies had correlations with some critical mutations that could be effectively targeted now.

Keyphrases

rheumatoid arthritis
high grade
genome wide
copy number
cancer therapy
dna methylation
drug delivery