Examining associations between genetic and neural risk for externalizing behaviors in adolescence and early adulthood.

Sarah J BrislinJessica E SalvatoreJacquelyn M MeyersChella KamarajanMartin H PlaweckiHoward J EdenbergSamuel KupermanJay TischfieldVictor HesselbrockAndrey P AnokhinDavid B ChorlianMarc A SchuckitJohn I NurnbergerLance BauerGayathri PandeyAshwini K PandeyJohn R KramerGrace ChanBernice Porjesznull nullDanielle M Dick

Published in: Psychological medicine (2023)

Both the EXT PGS and P3 amplitude were significantly associated with externalizing behaviors among EA young adults. However, these associations with externalizing behaviors appear to be independent of each other, suggesting that they may index different facets of externalizing.

Keyphrases

young adults
depressive symptoms
genome wide
dna methylation
gene expression
early life
functional connectivity
resting state