Molecular Weight of Hyaluronic Acid Has Major Influence on Its Efficacy and Safety for Viscosupplementation in Hip Osteoarthritis: A Systematic Review and Meta-Analysis.

Yen-Zung WuHsuan-Ti HuangCheng-Jung HoChia-Lung ShihChung-Hwan ChenTsung-Lin ChengYing-Chun WangSung-Yen Lin

Published in: Cartilage (2021)

Among different MWs of HA for treating hip OA, HMW HA injection demonstrated the best efficacy for up to 6 months after treatment without increased risk of adverse effects. Further studies with more comprehensive data and a higher level of evidence are required to prove our results.

Keyphrases

hyaluronic acid
total hip arthroplasty
knee osteoarthritis
electronic health record
rheumatoid arthritis
big data
case control
ultrasound guided
machine learning