Endothelial Microparticles Derived from Primary Pulmonary Microvascular Endothelial Cells Mediate Lung Inflammation in Chronic Obstructive Pulmonary Disease by Transferring microRNA-126.

Yiming MaXue HeXiangming LiuYingjiao LongYan Chen

Published in: Journal of inflammation research (2022)

The present study reveals that EMPs are capable of alleviating lung inflammation and transferring miR-126 can magnify the anti-inflammatory effect of EMPs, which may provide a novel therapeutic alternative for COPD.

Keyphrases

endothelial cells
oxidative stress
anti inflammatory
cell proliferation
chronic obstructive pulmonary disease
pulmonary hypertension
high glucose
lung function
vascular endothelial growth factor
cystic fibrosis