Caspase-independent hepatocyte death: A result of the decrease of lysophosphatidylcholine acyltransferase 3 in non-alcoholic steatohepatitis.
Keisuke KakisakaYuji SuzukiYudai FujiwaraAkiko SuzukiJo KanazawaYasuhiro TakikawaPublished in: Journal of gastroenterology and hepatology (2018)
Depletion of LPCAT3 in a mouse model of NASH leads to caspase-independent cell death, and LPCAT3 is a potential therapeutic target in NASH.