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Molecular Mechanism Analysis of the Effect of Hederagenin Combined with L-OHP on Chemosensitivity of AGS/L-OHP Based on Network Pharmacology.

Hongyue TangChao WangChenhao XingGuoxin LiangChang GuoXin LiuYanJie LiMingming Zhang
Published in: Current computer-aided drug design (2024)
Our findings suggest that HD may reduce the resistance of AGS/L-OHP cells to LOHP by regulating the PI3K/Akt signaling pathway.
Keyphrases
  • induced apoptosis
  • signaling pathway
  • cell cycle arrest
  • pi k akt
  • endoplasmic reticulum stress
  • epithelial mesenchymal transition
  • oxidative stress