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Cadinane sesquiterpenes from the stems and branches of Illicium ternstroemioides .

Jia YangJian-Pei ZhangRong-Mei GaoWen-Rui LiJing-Yu ZhangQian-Ru WangMi LiHai-Qiang WangGuo-Zhu SuLi LiYu-Huan LiRu-Bing WangXiao-Jing WangShuang-Gang Ma
Published in: Journal of Asian natural products research (2024)
Three new cadinane sesquiterpenes ( 1 - 3 ) and three known sesquiterpenes were isolated from the stems and branches of Illicium ternstroemioides A. C. Smith. The structures of the new compounds were elucidated by extensive analysis of spectroscopic and HRESIMS data. The structures of illiternins A-C ( 1 - 3 ) were confirmed by single crystal X-ray diffraction, allowing for the determination of their absolute configurations. Compounds 3 and 6 exhibited antiviral activity against Coxsackievirus B3 with IC 50 values of 33.3 and 57.7 μM, respectively.
Keyphrases
  • high resolution
  • molecular docking
  • electronic health record
  • big data
  • solid phase extraction
  • molecularly imprinted
  • dual energy
  • machine learning
  • crystal structure
  • data analysis
  • contrast enhanced