Testicular cancer disproportionally affects men of reproductive age making fertility an important aspect of testicular cancer survivorship. Men with testicular cancer have more semen parameter abnormalities and a higher incidence of infertility compared to the general population. All treatment options for testicular cancer negatively affect fertility with recovery rates varying by treatment. For these reasons, clinicians should offer sperm cryopreservation, ideally before orchiectomy to maximize the possibility of biologic paternity, if desired. Several innovations have positively impacted this space including direct-to-consumer cryopreservation and bench research demonstrating the feasibility of reintroducing testicular cells post-therapy.
Keyphrases
- papillary thyroid
- childhood cancer
- squamous cell
- germ cell
- rheumatoid arthritis
- lymph node metastasis
- healthcare
- stem cells
- signaling pathway
- mesenchymal stem cells
- type diabetes
- squamous cell carcinoma
- oxidative stress
- skeletal muscle
- cell death
- middle aged
- health information
- combination therapy
- social media
- cell cycle arrest
- pi k akt