Can chronic anti-tumour necrosing factor therapy and colic polyps overwhelm a normal functioning mitral valve? A case report of an endocarditis complicated by a ruptured intracranial mycotic aneurysm.
Karim KhadirDaniela MiricaNoemie LigotPhilippe Van de BornePublished in: European heart journal. Case reports (2021)
Immunosuppression from etanercept treatment was likely responsible for this unspecific clinical presentation and potentially devastating intracranial mycotic aneurysm. This complication is infrequently reported within 6 months of anti-tumour necrosing factor therapy initiation but occurred after more than 11 years of therapy in our patient. This case is a timely reminder of the clinical challenges of endocarditis in immunosuppressed patients and highlights a potential long-term complication of etanercept.
Keyphrases
- mitral valve
- rheumatoid arthritis
- coronary artery
- end stage renal disease
- chronic kidney disease
- newly diagnosed
- juvenile idiopathic arthritis
- stem cells
- mesenchymal stem cells
- case report
- systemic lupus erythematosus
- bone marrow
- climate change
- subarachnoid hemorrhage
- left atrial
- optical coherence tomography
- endovascular treatment