Intravenous tranexamic acid reduces complications following surgical treatment of pathologic fractures of the lower extremity.

Brandon S GettlemanKevin C LiuMary K RichardsonMatthew ChenArad TalehakimiNathanael D HeckmannLawrence MenendezAlexander B Christ

Published in: Journal of surgical oncology (2024)

Administration of IV TXA may be associated with a decreased risk of postoperative DVT without an increased risk of other complications. Orthopedic surgeons should consider the utilization of IV TXA in patients treated surgically for neoplastic pathologic fractures of the lower extremity.

Keyphrases

neoadjuvant chemotherapy
risk factors
locally advanced
patients undergoing
quality improvement
high dose
squamous cell carcinoma
radiation therapy
rectal cancer