Disconnectome of the migraine brain: a "connectopathy" model.

Marcello SilvestroAlessandro TessitoreGiuseppina CaiazzoFabrizio Scotto di ClementeFrancesca TrojsiMario CirilloFabrizio EspositoGioacchino TedeschiAntonio Russo

Published in: The journal of headache and pain (2021)

The imbalance between the need of investing resources to promote network efficiency and the need of minimizing the metabolic cost of wiring probably represents the mechanism underlying migraine patients' susceptibility to triggers. Such changes in connectome topography suggest an intriguing pathophysiological model of migraine as brain "connectopathy".

Keyphrases

resting state
end stage renal disease
white matter
functional connectivity
chronic kidney disease
newly diagnosed
prognostic factors
peritoneal dialysis
cerebral ischemia
brain injury
patient reported