Subchondral pressures and perfusion during weight bearing.
Michael BeverlyBarbara E MarksDavid W MurrayPublished in: Journal of orthopaedic surgery and research (2020)
Superimposed on a variable background IOP, increased perfusion and physiological loading caused a significant increase in subchondral IOP. Force was thereby transmitted through subchondral bone partly by hydraulic pressure. A falling IOP with repeat loading suggests that there is an intraosseous one-way valve. This offers a new understanding of subchondral perfusion physiology.