Limbal niche cells can reduce the angiogenic potential of cultivated oral mucosal epithelial cells.

Chao-Ye DuanHua-Tao XieXin-Yue ZhaoWen-Han XuMing-Chang Zhang

Published in: Cellular & molecular biology letters (2019)

LNCs could substitute 3T3 cells for expanding OMECs in vitro, and the COMECs obtained in this system are less likely to induce postsurgical neovascularization, which provides an alternative option for an ex vivo culture system and promotes the application of COMET.

Keyphrases

vascular endothelial growth factor
induced apoptosis
cell cycle arrest
endoplasmic reticulum stress
oxidative stress
ulcerative colitis
signaling pathway
diabetic retinopathy