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Exposure to perfluoroalkyl and polyfluoroalkyl substances and pediatric obesity: a systematic review and meta-analysis.

Brianna FrangioneSapriya BirkTarek BenzouakLaura A Rodriguez-VillamizarFatima KarimRose DugandzicPaul J Villeneuve
Published in: International journal of obesity (2005) (2023)
Our review found no evidence of a positive association between prenatal PFAS exposure and pediatric obesity, whereas an inverse association was found for postnatal exposure. These findings should be interpreted cautiously due to the small number of studies. Future research that can inform on the effects of exposure mixtures, the timing of the exposure, outcome measures, and the shape of the exposure-response curve is needed.
Keyphrases
  • metabolic syndrome
  • insulin resistance
  • type diabetes
  • pregnant women
  • drinking water
  • preterm infants
  • skeletal muscle
  • body mass index
  • ionic liquid
  • childhood cancer