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Neurotoxicity and Behavioral Alterations Following Subchronic Administration of Aqueous Extract of Erythrophleum Ivorense Stem Bark in Mice.

Olamide Elizabeth AdebiyiOluwasina AjayiFunmilayo Eniola Olopade
Published in: Basic and clinical neuroscience (2021)
Erythrophleum ivorense administration altered motor coordination, learning and memory, and grip strength in mice dose-dependently. It also caused disruption of granule cells layer, loss of Purkinje cells, and altered cerebellar anatomy leading to motor deficits in mice.
Keyphrases
  • induced apoptosis
  • high fat diet induced
  • cell cycle arrest
  • oxidative stress
  • endoplasmic reticulum stress
  • type diabetes