Tuberculosis-Associated Respiratory Disability in Children, Adolescents, and Adults: Protocol for a Systematic Review and Individual Participant Data Meta-Analysis.

An individual participant data meta-analysis allows for data harmonization to help overcome limitations of individual studies and aggregate meta-analysis, including small sample size, heterogeneity, and limited reporting of subgroups, such as age and other risk factors.We will be able to identify weaknesses in current reporting and recommend standards to support high-quality data collection and facilitate pooling of data.Key limitations include authors' willingness to share data, representativeness of data contributed, and missing data.We will build an ongoing data collection platform to allow updating of evidence.Results will have implications for public health, clinical trial design, and clinical practice to support TB survivors.