Rheumatoid factor isotypes in rheumatoid arthritis diagnosis and prognosis: a systematic review and meta-analysis.

Francesca Motta Nicola BizzaroDavide GiavarinaFranco FranceschiniMaria InfantinoBoaz PaltererGian Domenico SebastianiCarlo Francesco Selmi

Published in: RMD open (2023)

Testing RF allows the highest sensitivity, while IgA isotype the highest specificity and positive likelihood ratio for RA diagnosis. On the other hand, determination of RF isotypes dose not allow prognostic information, as data are limited and heterogeneous.

Keyphrases

rheumatoid arthritis
disease activity
ankylosing spondylitis
interstitial lung disease
systemic lupus erythematosus
big data
health information
machine learning
systemic sclerosis
mass spectrometry