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Reliability and minimal detectable change of dynamic temporal summation and conditioned pain modulation using a single experimental paradigm.

Matthieu VincenotLouis-David BeaulieuLouis GendronSerge MarchandGuillaume Leonard
Published in: PloS one (2024)
Our approach seems well-suited to clinical use. Although our method shows equivalent relative and absolute reliability compared to other protocols, we found that the reliability of endogenous pain modulation mechanisms is vulnerable, probably due to its dynamic nature.
Keyphrases
  • chronic pain
  • pain management
  • neuropathic pain
  • spinal cord