Circulating tumor cells and survival in abiraterone- and enzalutamide-treated patients with castration-resistant prostate cancer.
Bram De LaereSteffi OeyenPeter Van OyenChristophe GhyselJozef AmpePiet OstWim DemeyLucien HoekxDirk SchrijversBarbara BrouwersWillem LybaertEls EveraertPiet Van KerckhoveDaan De MaeseneerMichiel StrijbosAlain BolsKaren FransisNick BeijeInge de KruijffValerie van DamAnja BrouwerPieter-Jan van DamGert Van den EyndenAnnemie RuttenStefan SleijferJean VandebroekSteven Van LaereLuc DirixPublished in: The Prostate (2018)
CTC dynamics during therapy are associated with PSA response and provide independent clinical prognostication over PSA declines. Hence the study demonstrates the pharmacodynamic properties of CTCs.