Visible-Light-Induced C-F and C-N Bond Cleavage for the Synthesis of gem -Difluoroalkenes.

Herein, we describe a novel and efficient photoredox catalytic radical addition/defluoroalkylation coupling reaction between primary amines and trifluoromethyl-substituted alkenes. A series of gem -difluoroalkenes were synthesized via C-N bond cleavage of α-3°, α-2°, and α-1° amines under visible light irradiation. This reaction is characterized by a broad substrate scope and good functional group tolerance.