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RSPO4 is a potential risk gene of stages III-IV, grade C periodontitis through effects on innate immune response and oral barrier integrity.

Avneesh ChopraJiahui SongJanuary WeinerHuseyin Gencay KeceliPervin R DincerRaquel CruzAngel CarracedoJuan Blanco-CarriónHenrik DommischArne S Schaefer
Published in: Journal of clinical periodontology (2022)
RSPO4 is a potential periodontitis risk gene and modifies host defence and barrier integrity.
Keyphrases
  • immune response
  • genome wide
  • copy number
  • dendritic cells
  • human health
  • gene expression
  • risk assessment
  • dna methylation
  • climate change
  • transcription factor
  • inflammatory response