Virus matrix interference on assessment of virucidal activity of high-touch surfaces designed to prevent hospital-acquired infections.
Sadru-Dean WaljiMark R BruderMarc G AucoinPublished in: Antimicrobial resistance and infection control (2021)
Ion leaching was associated with virucidal activity in both wet and dried virus conditions. Soiling protected the virus by quenching metal ions, and not by inhibiting leaching. The composition of the solution containing virus plays a critical role in evaluating the virucidal activity of surfaces and surface coatings.