Causes and consequences of major depressive disorder: An encompassing Mendelian randomization study.
Joëlle A PasmanJacob BergstedtArvid HarderTong GongYing XiongSara HäggFang FangJorien L TreurKarmel W ChoiPatrick F SullivanYi LuPublished in: medRxiv : the preprint server for health sciences (2024)
This study provides a systematic overview of traits putatively causally related to MDD, confirming previous findings as well as identifying new associations. Our results highlight the importance of MDD as a risk factor cross-cutting across medical, functional, and psychosocial domains and emphasize the need for concerted efforts at reducing this highly prevalent disorder.