Immune Checkpoint Inhibitor Associated Central Nervous System Autoimmunity.

Cristina Valencia SanchezElia SechiDivyanshu DubeyEoin Patrick FlanaganAndrew McKeonSean J Pittock Anastasia Zekeridou

Published in: European journal of neurology (2023)

One third of ICI-related CNS-autoimmunity patients have unfavorable outcomes related to their clinical presentation. Relapses may occur after ICI re-challenge. Neural autoantibodies are often present, more commonly in patients with NET.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
peritoneal dialysis
prognostic factors
systemic lupus erythematosus
blood brain barrier
skeletal muscle
adipose tissue
patient reported outcomes
weight loss
drug induced