Severity of Illness Caused by Severe Acute Respiratory Syndrome Coronavirus 2 Variants of Concern in Children: A Single-Center Retrospective Cohort Study.

Priya R EdwardRamon Lorenzo-RedondoMegan E ReynaLacy M SimonsJudd F HultquistAmi B PatelEgon Anderson Ozer William J Muller Taylor Heald-SargentMatthew McHughTaylor DeanRaj M DalalJordan JohnShannon C ManzLarry K Kociolek

Published in: Journal of the Pediatric Infectious Diseases Society (2022)

Compared to non-VOC COVID-19, the gamma VOC was independently associated with increased COVID-19 severity, as was omicron in children without SARS-CoV-2 immunization or prior COVID-19 infection. SARS-CoV-2 vaccination and prior COVID-19 prevented severe outcomes during the omicron surge.

Keyphrases

sars cov
respiratory syndrome coronavirus
coronavirus disease
young adults
early onset
type diabetes
gene expression
copy number
metabolic syndrome
dna methylation