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Thresholds of glycemia, insulin therapy, and risk for severe retinopathy in premature infants: A cohort study.

Elsa Kermorvant-DucheminGuylène Le MeurFrank PlaisantLaetitia Marchand-MartinCyril FlamantRaphaël PorcherAlexandre LapillonneSylvain ChemtobOlivier ClarisPierre-Yves AncelJean-Christophe Rozé
Published in: PLoS medicine (2020)
In this study, we observed that exposure to high glucose concentration is an independent risk factor for severe ROP, and we identified cutoff levels that are significantly associated with increased risk. The clinical impact of avoiding exceeding these thresholds to prevent ROP deserves further evaluation.
Keyphrases
  • high glucose
  • endothelial cells
  • type diabetes
  • early onset
  • drug induced
  • metabolic syndrome
  • insulin resistance
  • skeletal muscle
  • cell therapy
  • replacement therapy
  • breast cancer risk