Population, Clinical, and Scientific Impact of National Cancer Institute's National Clinical Trials Network Treatment Studies.
Joseph M UngerMichael LeBlancSuzanne GeorgeNorman WolmarkWalter J CurranPeter J O'DwyerMitchell D SchnallRobert S MannelSumithra J MandrekarRobert C GrayFengmin ZhaoMariama BahRiha VaidyaCharles D BlankePublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2022)
NCTN randomized trials have been widely cited and are routinely included in clinical guidelines. Moreover, their conduct has predicted substantial improvements in overall survival in the United States for patients with oncologic disease, suggesting they have contributed meaningfully to this nation's health. These findings demonstrate the critical role of government-sponsored research in extending the lives of patients with cancer.